منابع مشابه
Simian virus 40 and human disease.
Received 11 August 2004; accepted 11 August 2004; electronically published 16 November 2004. Reprints or correspondence: Dr. Keerti Shah, Dept. of Microbiology and Immunology, Johns Hopkins School of Public Health, 615 North Wolfe St., Baltimore, MD 21205 (kvshah @jhsph.edu). The Journal of Infectious Diseases 2004;190:2061–4 2004 by the Infectious Diseases Society of America. All rights reserv...
متن کاملSimian virus 40 and the human mesothelium.
D tumor viruses have evolved to replicate, not to cause tumors. Their carcinogenic effect depends on the blocking of the lytic cycle and the ability of latently infected, potentially proliferative cells to escape immune surveillance. These conditions can be satisfied by accidental ‘‘experiments of nature’’ or by the artifices of laboratory experimentation. Potentially tumorigenic papovaviruses ...
متن کاملSimian Virus 40 (SV40) and Human Cancers
Simian virus 40 (SV40) contaminated the early poliovirus vaccines used throughout much of the world during the late 1950’s and early 1960’s. SV40 is oncogenic in rodents and can transform human cells in vitro. Most epidemiologic studies, however, have failed to detect increased risks of cancer among those exposed to SV40-contaminated poliovirus vaccines, even after more than 30 years of follow-...
متن کاملSusceptibility of human cell strains to transformation by simian virus 40 and simian virus 40 deoxyribonucleic acid.
Marked differences were found in the susceptibility of human fibroblasts to transformation by simian virus 40 (SV40). Highly susceptible cell strains were derived from patients with diseases associated with chromosomal abnormalities and a high incidence of tumors. In the present study, SV40 transformation-susceptible cell strains were not found to have a generalized increase in viral sensitivit...
متن کاملShort papers Simian virus 40 and human pleural mesothelioma
Background—An aetiological role for Simian virus 40 (SV40) in malignant mesothelioma has been suggested from studies in the USA and the UK but results have been conflicting. A study was undertaken to look for evidence of SV40 in stored tissue samples from pleural mesotheliomas. Methods—DNA was extracted from paraffin embedded tissue. The presence of DNA was established by amplification of a 250...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2004
ISSN: 0022-1899,1537-6613
DOI: 10.1086/425999